Previously, transcriptomic studies have shown that Brucella infection does not induce expression of c-fos during late infection (Eskra et al., 2003; Cha et al., 2013; Hop et al., 2017a); therefore, little attention has been given to the immunological role of c-Fos during studies of Brucella pathogenesis. The gene discussed is FOS; the disease is infection.