BRCA2 and cancer: We have detected this mutation 10 times and it is reported in LOVD at least 49 times (including 7 from our laboratory) (18). The family history is relatively scarce in information, with a sister with breast cancer and the father with prostate cancer. The daughter and one of the sons tested normal for the mutation. Considering the origin of this mutation it may be the case that the cancer diagnosis from the Jewish side could be phenocopies, and for this reason the prevalence for BRCA2 non AJ was also calculated non including this case.