TIPE2 and metastatic malignant neoplasm in the lymph nodes: As shown in Table 1, TIPE2 expression was negatively associated with tumor size (P = 0.0002), capsule infiltration (P = 0.0085), peripheral infiltration (P = 0.0036) and tumor T stage (P = 0.0001), while no significant association was shown between TIPE2 expression and age (P = 0.3403), gender (P = 0.3841) and lymph node metastasis (P = 0.0941).