VEGFA and atherosclerosis: It has been reported that Rhodiola rosea and Shexiang Baoxin Pill can promote angiogenesis and increase myocardial microvessel density by increasing the expression levels of HIF-1α, VEGF, VEGFR2, and CD34 while inhibiting vessel growth and decreasing plaque area in atherosclerosis by reducing these indexes in the aorta [56, 57].