For instance, the eukaryotic translation initiation factor 4E (eIF4E) and 4G (eIF4G) in eukaryotes are essential host factors required for infection by many viruses including Potyvirus and mutations of these gene results in recessive resistance in crop plants (Gal-On et al., 2000; Kang et al., 2005; Truniger and Aranda, 2009; Bastet et al., 2017). This evidence concerns the gene EIF4E and infection.