TNF and endometriosis: Moreover, transient inhibition or reduction of miR-223 expression exacerbated endometriosis, as indicated by the histological indices, increased NLRP3, IL-1β, IL-6, and TNF-α secretion, as well as the IL-1β-inducible chemokines CXCL1 and CXCL2 mRNA transcripts (Figures 6C–G).