Also, PGE2 (via IL-10 production) increases the phagocytic activity of Balb/c mice-derived B-1CDP cells (a particular B-1 cell type with phagocytic ability; Borrello and Phipps, 1999), but it impairs the ability of the mice to resist the infection (Arcanjo et al., 2015). The gene discussed is IL10; the disease is infection.