High expression of SOX2 has been correlated with tumor progression of oral squamous cell carcinoma (Fu et al., 2016), hepatocellular carcinoma (Zhao et al., 2015), colorectal cancer (Zheng et al., 2017), glioblastoma (Dong et al., 2017) and others. The gene discussed is SOX2; the disease is hepatocellular carcinoma.