STAT3 and carcinoma of esophagus: It is reported that STAT3 is highly active in myeloma cell lines (Levy and Darnell, 2002), as well as in head and neck squamous cell (Sriuranpong et al., 2003; Adachi et al., 2012), breast (Behera et al., 2010; Lei et al., 2016), brain (Garg et al., 2017), gastric (Zhang et al., 2017), lung (Gritsko et al., 2006; Levy and Granot, 2006; Yu et al., 2009; Looyenga et al., 2012; Assi et al., 2014), and esophageal carcinomas (Liu et al., 2015).