STAT3 protein is a key regulator of human cancers, contributing to proliferation, uncontrolled differentiation, survival, invasion, tumorigenesis, and resistance to chemotherapy (Buettner et al., 2002; Yu and Jove, 2004; Haura et al., 2005; Grivennikov et al., 2009; Wang et al., 2011; Yu et al., 2014; Huynh et al., 2017). This evidence concerns the gene STAT3 and cancer.