To determine the relationship between Aβ and resolution of inflammation, microglia cells were treated with Aβ42, and the result showed that FPR2, α7nAChR, and (PPAR)-δ was downregulated by Aβ42 treatment, indicating the expression of FPR2 is correlated with resolution of inflammation and dysfunction in AD (Zhu et al., 2015). Here, FPR2 is linked to Alzheimer disease.