LRRK2 and Parkinson disease: This is the case of PD-related proteins, such as α-synuclein (α-syn), Parkin and LRRK2, which co-chaperon SVs’ trafficking and DA release by interacting physically with Rabs, SNAREs and Endophilin-A (Burré et al., 2010; Cao et al., 2014; Soukup et al., 2016; Shi et al., 2017; Ryskalin et al., 2018a).