Tauopathies, characterized by tau protein accumulation, include Alzheimer’s disease (AD), some variants of frontotemporal lobar degeneration (FTLD), frontotemporal dementia with parkinsonism linked to chromosome-17 (FTLD-17), corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), argyrophilic grain disease (AGD), and chronic traumatic encephalopathy (CTE). This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.