To investigate the role of neutrophils in tumor-initiation, we followed up on a published zebrafish model of glioblastoma that used the Gal4-UAS system to drive oncogenic human KrasG12V under the zebrafish astrocyte-specific gfap promoter and formed tumors as early as 6 months post-fertilization25. Here, LGALS4 is linked to glioblastoma.