Two different EpCAM negative cells lines were used to observe potential changes in different cell types: human epithelial cell line HEK 293 T (Fig. 5a,b) and CRISPR/Cas EpCAM-knockout colorectal adenocarcinoma cell line HCT8 #L1320 (Supplementary Fig. 4). The gene discussed is EPCAM; the disease is colorectal adenocarcinoma.