Among them, 13 proteins correlated with clinicopathological parameters and of these proteins, eight proteins were identified in neoplastic islands (ACTR2, CSTB, COL1A2, LTA4H, PGK1, NDRG1, S100A8, S100A9) and five proteins were identified in tumor stroma (COL6A1, FSCN1, ITGAV, MB, THBS2) (Table 1). This evidence concerns the gene ACTR2 and neoplasm.