Among other IHC markers, STAT6 nuclear staining was detected in all cases except for one (14/15, 93.3%), a finding consistent with literature data.[15] Rare STAT6-negative SFT/HPC are possible and in these cases diagnosis should be based on a careful revision of tumour morphology and using other markers like CD34, Bcl-2 and CD99. This evidence concerns the gene BCL2 and neoplasm.