However, the replicative potential of the Cancer and resistant Cancer balances out the negative effect of the IFN-γ leading to an oscillatory tumor-relapsing behavior, whereas the slowly replicating stem and resistant cells sub-populations gradually get eliminated from the tumor due to the high production of the IFN-γ cytokine (Fig 3J and 3K). The gene discussed is IFNG; the disease is neoplasm.