FGFR3 and colorectal carcinoma: FGFR3 mRNA overexpression was significantly associated with reduced overall survival (p=0.0152, HR=3.14 [1.19-8.31]; Figure 3, Table 4 ) and worse cancer specific survival (p=0.00497, HR=3.8 [1.4-10.35]; not shown) in metastasized CRC.