SYNGAP1 and Intellectual disability: Further molecular testing for non-syndromic intellectual disability genes found a likely pathogenic mutation in <i>SYNGAP1</i> (NM_006772.2:c.3722_3723del).<h4>Conclusions</h4>This study indicates that complex rearrangements involving an unbalanced chromosome derived from chromoanasynthesis can be familial and should be not be presumed pathogenic.