The association for rs2231142 in ABCG2 was significantly higher in CKD patients compared to the results from the general population (effect 0.4 mg/dl in CKD vs. 0.22 mg/dl in population-based studies, p-value for difference = 1.5E-03; Supplemental Table 4). The gene discussed is ABCG2; the disease is chronic kidney disease.