Independent of its protein-coding capacity, MYEOV transcript exerts its pro-metastatic function via abrogating the suppression of TGFBR2 and Ubiquitin specific protease 15 (USP15) expression by miR-30c-2-3p, leading to constitutive activation of TGF-β signaling and tumor progression in NSCLC. Here, TGFBR2 is linked to non-small cell lung carcinoma.