Myeloma overexpressed gene (MYEOV) locates in chromosome (chr)11q13.3, a region of cancer-associated genomic amplification [13–16], has been reported to be predominantly overexpressed and contribute to tumorigenesis in many human cancer types, including multiple myeloma [17], neuroblastoma [18], esophageal squamous cell carcinoma [19], breast cancer [20], gastric cancer [21], and colon cancer [22]. This evidence concerns the gene MYEOV and plasma cell myeloma.