The example of bryostatin (Bry-1), a potent modulator of PKC, initially isolated from the extract of Bugulaneritina, is emblematic of marine bioactive compounds’ potential, since Bry-1 is exploited in, according to the classic concept, different non-correlated diseases, such as cancer, HIV, and neurodegenerative diseases [84]. This evidence concerns the gene PRRT2 and neurodegenerative disease.