Conversely, the following factors were significantly associated with higher overall survival: HCC etiology such as HCV infection, platelet count, absence of cirrhosis, patients receiving antiviral therapy for viral hepatitis, absence of macrovascular and microvascular invasions, tumor size <5 cm, BCLC stage 0-A, absence of HCC recurrence, and the presence of LC3 expression in HCC tissues or ANT tissues. This evidence concerns the gene MAP1LC3A and Cirrhosis.