Differences between tumor types were most pronounced for regulatory T-cells (Foxp3+ cells, Figure 3D) with more than half of lung adeno (LUAD), head and neck squamous (HNSC), stomach adenocarcinoma (STAD) and esophageal (ESCA) cancer samples having Foxp3-hot topographies. The gene discussed is FOXP3; the disease is gastric adenocarcinoma.