SHCBP1 and non-small cell lung carcinoma: To further validate the clinical significance of SHCBP1 in NSCLC, clinical information collected from 207 NSCLC patients (Supplementary Table S7) was analyzed, and as expected, we found that the SHCBP1 protein level positively correlated with NSCLC clinical staging (P < 0.001) and T-, N-, and M-classification (P < 0.001, P = 0.035, and p < 0.001, respectively) (Supplementary Table S8).