In support of its oncogenic role in NSCLC, SHCBP1 was significantly up-regulated in the eight NSCLC specimens as compared to the corresponding adjacent non-cancerous lung tissue, in both a large cohort of NSCLC patients collected in the TCGA dataset and a panel of NSCLC cell lines compared with primary normal lung epithelial (NLE) cells (Fig. 7a–c). The gene discussed is SHCBP1; the disease is non-small cell lung carcinoma.