Of the cell surface receptors predicted by CRAFT to influence the expression one or more candidate epilepsy module, we chose to validate Csf1R because of an absence of prior information connecting Csf1R to epilepsy and the availability of a tool compound (PLX3397) by which to test CRAFT’s predictions related to Csf1R’s regulation of module 18 (and by extension module 18's relationship to epilepsy). This evidence concerns the gene CSF1R and epilepsy.