Of the many membrane receptors predicted to significantly influence the expression of module genes in a direction-specified manner, macrophage colony-stimulating factor (M-CSF) receptor (also known as colony-stimulating factor 1 receptor encoded by the Csf1R gene in the mouse) was predicted to be a regulator of two of the seven prioritized candidate epilepsy modules (modules 18 and 22, P = 0.017 and P = 0.031, respectively). This evidence concerns the gene CSF1R and epilepsy.