FBXW7 and gastric cancer: There are three FBW7 isoforms identified in human genome (α, β, and γ)20, to determine if there is any specificity for FBW7 isoforms to interact with, and to promote Brg1 ubiquitination, we examined the expression of three isoforms in gastric cancer cells and revealed FBW7α as the most abundant isoform (Supplementary Figure 2a).