However, it is important to note that CA9 mRNA was found to be expressed in normal liver and biliary tissues [16] while CD147, a member of the immunoglobulin superfamily also called Basigin (BSG), is ubiquitously expressed in 15 distinct normal tissues [61] and can serve as a marker of renal fibrosis or IgA nephropathy [62]. This evidence concerns the gene BSG and renal fibrosis.