PGF and obesity due to melanocortin 4 receptor deficiency: Although we confirmed preeclampsia risk factors previously reported in a heterogeneous BMI population, notably raised mean arterial blood pressure and a reduced concentration of PlGF in early second trimester, we also report that PlGF, increasingly used in prediction or diagnosis of preeclampsia [18], [19], was not associated with preeclampsia in women with obesity who developed GDM.