This cell line also express a high level of many metabolic targets consistently upregulated in HCC patients microarrays (e.g. AKR1B10, SQLE, LYZ, PLCB1) [13], thus raising the question of whether HUH7 could be a crucial surrogate for identifying novel HCC metabolic biomarkers. The gene discussed is MIR7-3HG; the disease is hepatocellular carcinoma.