It was reported that MIR31HG was localized in the cytoplasm of pancreatic ductal adenocarcinoma cells [12], and our subcellular fractionation and qRT-PCR assay also determined the similar result in HCC cells, suggesting that MIR31HG might play a role in posttranscriptional level. This evidence concerns the gene MIR31HG and hepatocellular carcinoma.