CPS1 and hepatocellular carcinoma: Yin ZF et al. [44–46] used flow cytometry to identify circulating HCC cells using biomarkers such as Hep Par 1, CK and CPS1 and demonstrated that the unique magnetic circulating HCC cell separation system mediated by the interaction of the asialoglycoprotein receptor (ASGPR) with its ligand could be used for the specific and efficient detection of circulating HCC cells.