A recent research by Turrell et al., using Ras and mutant p53-driven lung carcinoma mouse model, extended these findings with a stronger induction of the wt p53 expression in the presence of mutant p53 – demonstrating that wt p53, though still at lower level than mutant p53, largely avoids and suppresses the effects of mutant p53 on transcription and tumor growth [23]. This evidence concerns the gene TP53 and lung carcinoma.