The increase of TH and BAP was paralleled by a significant increase of TNF-alpha and IL-6 in septic animals in comparison to controls, and a positive correlation was observed at 1-hour post-CLP between TH and BAP, TH and TNF-alpha, and BAPs and IL-6 [52], suggesting mutual interactions between inflammatory pathways and oxidative stress during neonatal sepsis. The gene discussed is IL6; the disease is Neonatal sepsis.