IL4 and Sepsis: The comparison of immune response during sepsis in preterm newborn ≥ 32 or <32 weeks of gestational age showed that mediators of innate immune response, as C-reactive protein (CRP) and SC5b-9, are increased in both groups, but proinflammatory cytokines as interferon-gamma, TNF-alpha, and IL-6 are upregulated only in the subgroup with gestational age ≥ 32 weeks, while both groups showed increased levels of anti-inflammatory cytokines, as IL-4 and IL-10 [14].