COL6A1 and Ullrich congenital muscular dystrophy: Similar defects were found in muscle biopsies of UCMD and BM patients (Angelin et al., 2007; Merlini et al., 2008a; Grumati et al., 2010), and following the demonstration that reactivation of autophagy by different means is beneficial in recovering the structural and functional defects of Col6a1-/- mice, a pilot clinical trial in UCMD and BM patients by 1-year low-protein diet was successful in reactivating autophagy (Castagnaro et al., 2016).