Several studies, including studies of TPP-docetaxel conjugates and TPP-photosensitizer-loaded albumin nanoparticles (Battogtokh and Ko, 2017; Battogtokh et al., 2018), paclitaxel, cisplatin or Dox-α-TOS conjugate-loaded lipid nanoparticles (Mallick et al., 2015), and DQA-Dox-loaded pH-responsive micelles (Song et al., 2015), have revealed dual-targeting to the tumor area and mitochondria. This evidence concerns the gene ALB and neoplasm.