In line with this phenotype of a relative brain MR excess, studies with mouse mutants overexpressing MR in limbic forebrain revealed enhancement of memory (Ferguson and Sapolsky 2007; Lai et al. 2007; Kolber et al. 2008), perseveration of learned behavior (Harris et al. 2013), and reduction of anxiety (Rozeboom et al. 2007). Here, NR3C2 is linked to Anxiety.