The quantification of our Drp1 staining showed that the AD patient fibroblasts (both sAD and PSEN1) have less Drp1 specifically at their mitochondria (controls 100 ± 11.13, sAD 32.77 ± 11.63, PSEN1 36.58 ± 9.35; p < 0.01; Fig. 4B). Here, DNM1L is linked to Alzheimer disease.