In this study, we did not investigate any of the post-translational modifications of Drp1 or any of the other known pathways that can affect Drp1 localization or phosphorylation state (including AMPK, protein kinase A and ERK); therefore, this should be investigated further to fully elucidate the mechanism of action of UDCA in AD. This evidence concerns the gene DNM1L and Alzheimer disease.