ESR2 and renal cell carcinoma: In addition to detecting the expression of EMT markers, we further examined a group of EMT/metastasis‐related miRNAs using a quantitative PCR assay and the results revealed that microRNAs (miRNA, miR) such as miR126, miR145 and miR155 were up‐regulated in RCC cells, with higher ERβ expression in both cell lines (Fig. 4D).