TGFB1 and thyroid gland carcinoma: Overall, the results of the present study have shown that Pard3 inhibited TGF-β1-induced cell EMT and invasion, concomitant with miR-483 downregulating Pard3 in thyroid carcinoma cells, to activate Tiam/Rac1 signaling and promoting EMT, as well as cell migration and invasion.