Levels of endothelial- derived microparticles such as CD105+, PECAM-1, 62E+ and CD106+ as well as platelet-derived microparticles including P-selectin, fibrinogen, TF have been reported to be significantly higher in T2DM patients as compared to healthy controls [79, 128–130]. Here, PECAM1 is linked to type 2 diabetes mellitus.