ADAMTS9 and central nervous system cancer: ADAMTS9-AS2 was the second key lncRNA we identified and is an antisense overlapping lncRNA located upstream from ADAMTS9, a newly described tumor suppressor gene.[18] Yao et al examined experimental data to suggest that a decrease in lncRNA ADAMTS9-AS2 expression associated with the diagnosis, clinicopathological characteristics, and prognosis of glioma.