LTA4H and meningeal tuberculosis: Leukotriene A4 hydrolase (LTA4H) genotype has been shown to affect the inflammatory phenotype and clinical response to dexamethasone therapy in Vietnamese adults with TBM: CC homozygotes have a hypoinflammatory response, CT heterozygotes have a moderate inflammatory response, whereas TT homozygotes have a hyperinflammatory response.