ELANE and cancer: This study describes the broad-spectrum anti-cancer activities of EgKI-1 which is the first anti-cancer molecule identified from the cestode E. granulosus. Although we hypothesized based on our previous studies [16] that the potent neutrophil elastase activity of EgKI-1 would result in cancer cell regression, the in vitro culture medium we employed did not contain neutrophils or neutrophil elastase (S2 Fig).