CACNA1A and migraine, familial hemiplegic, 1: Mutations in the CACNA1A gene have been found to be responsible for three disorders with autosomal dominant inheritance: i) Episodic Ataxia 2 (EA2; MIM: 108500), ii) familial hemiplegic migraine type 1 (FHM1; MIM: 141500), and iii) spinocerebellar ataxia type 6 (SCA6; MIM: 183086).