Our results also revealed an increase in AMP/ATP ratio in response to suppression of FABP5 and induction of apoptosis and cell cycle arrest through the AMPK-FOXO3A signaling pathway in PCa cells (Figure 7B), strongly suggesting that FABP5 regulates cell growth and mitochondrial functions that is essential for energy metabolism in PCa cells. The gene discussed is FABP5; the disease is posterior cortical atrophy.