PDPK1 and posterior cortical atrophy: In PCa cells, activation of PPARβ/δ with GW0742 resulted in an increase in the mRNA levels of ADRP, PDPK1 and ILK, a PPAR (β/δ and γ) target gene [56], while FABP5 expression level had no effect (Figure 3B, 3C and Supplementary Figure 3A).