Because a previous study has shown that the nuclear entrapment of p210BCR-ABL induces apoptosis of CML cells [42], we hypothesized that p210BCR-ABL-induced cell death observed in 32D/TetOff-p210 cells may be caused by the nuclear entrapment of p210BCR-ABL. The gene discussed is ABL1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.