HRH3 and Anxiety: Figure 6 shows the observed effects of subchronic systemic injection of saline or the H3R antagonist DL77 (5, 10, or 15 mg/kg, i.p.)on the anxiety parameters of VPA-exposed mice tested in the EPM, namely, the percentage of time spent in open arms (Fig. 6A), the number of entries into open arms (Fig. 6B), and locomotor activity expressed as the number of entries into closed arms (Fig. 6C).