Additionally, a 1.5–2-fold concurrent increase in IL-10 cytokines with TB/HIFU (180.5455 ± 16.64 ng/ml) and Salmonella/HIFU Salmonella ± HIFU (121.84 ± 16.10) compared to HIFU (79.7 ± 5.09) alone was also noted (Fig. 6c). The gene discussed is IL10; the disease is tuberculosis.