While our previous data on healthy mice corroborated an increase of myeloid markers in the BM of Ats1-KO mice, now we detected that the induction of B16F1 tumours provoked a clear upregulation of genes as Cd11b and Cd163 but just in WT animals (Fig. 6b), without major alteration on the Ats1-KO background, suggesting the blockade of the mobilization of these populations in an Adamts1-deficient scenario. The gene discussed is ITGAM; the disease is neoplasm.